CCG-257081

SKU: orb1697931

Description

CCG-257081 (MRTF/SRF-IN-1) is a small molecule inhibitor targeting the Rho/MRTF/SRF pathway. It has demonstrated efficacy in preclinical models, such as reducing bleomycin-induced pulmonary fibrosis in mice, supporting its research applications in fibrosis and cancer prevention studies.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1922098-90-5
• MW: 473.87
• Purity: >99.99% (May vary between batches)
• Formula: C₂₄H₁₉ClF₃N₃O₂
• SMILES: C(=O)(C=1C=C(C=C(F)C1)C=2C=CN=CC2)N3CC(C(NC4=CC=C(Cl)C=C4)=O)CC(F)(F)C3
• Target: Rho,Ras
• Solubility: DMSO:50 mg/mL (105.51 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (10.55 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CCG257081, CCG-257081, CCG 257081, MRTF/SRF-IN-1, Rho, Ras

Compound Identifiers

PubChem CID

121317995