CCF0058981

SKU: orb1301167

Description

CCF0058981

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 2708934-53-4
• MW: 442.9
• Purity: 98.94%
• Formula: C₂₄H₁₉ClN₆O
• SMILES: C(C(N(CC1=CC(Cl)=CC=C1)C2=CC=C(C=C2)C3=CN=CN3)=O)N4C=5C(N=N4)=CC=CC5
• Target: SARS-CoV,Virus Protease
• Solubility: DMSO:1 mg/mL (2.26 mM)

Bioactivity

• In Vitro:
  CCF0058981 (CCF981) demonstrates inhibition of cytopathic effect (CPE) and plaque reduction in vitro viral replication, with EC50 values of 497 nM and 558 nM, respectively . Additionally, its 50% cytotoxic concentration (CC50) in the CPE antiviral assay exceeds 50 μM . The compound has a half-life (T1/2) of 21.1 minutes and a clearance rate (CLint) of 141 mL/min/kg in human liver microsomes .

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CCF 0058981, CCF0058981, CCF-0058981, SARSCoV, SARS-CoV-2

Compound Identifiers

PubChem CID

156027237