CBX-12

SKU: orb2814373

Description

CBX-12 is an Exatecan-based peptide-drug conjugate (PDC) that utilizes a pH-sensitive pHLIP for antigen-independent tumor targeting and an auto-cleavable linker for payload release. It demonstrates antitumor activity in research models by inhibiting topoisomerase I (TOP1) in cancer cells, applicable for in vitro and in vivo oncology studies.

Research Area

Molecular Biology

Key Properties

• Target: Topoisomerase
• MW: 3629.05
• Formula: C₁₆₉H₂₄₀FN₃₅O₄₉S₂

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Topoisomerase