cBu-Cit-PROTAC BRD4 Degrader-5

SKU: orb2564536

Description

cBu-Cit-PROTAC BRD4 Degrader-5 is a small molecule PROTAC that induces potent degradation of the BRD4 protein. It demonstrates efficacy in cellular models of breast cancer, independent of HER2 status, making it a useful chemical probe for oncology research and targeted protein degradation studies.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2417369-73-2
• MW: 1628.31
• Formula: C₇₉H₉₉ClN₁₆O₁₆S₂
• SMILES: CC=1C2=C(N3C([C@H](CC(NCCOCCOCCOCC(N[C@H](C(=O)N4[C@H](C(NCC5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](OCNC(OCC7=CC=C(NC([C@@H](NC(=O)C8(C(NCCCCCN9C(=O)C=CC9=O)=O)CCC8)CCCNC(N)=O)=O)C=C7)=O)C4)[C@@](C)(C)C)=O)=O)N=C2C%10=CC=C(Cl)C=C%10)=NN=C3C)SC1C
• Target: PROTAC-Linker Conjugates for PAC,PROTAC-Linker Conjugates for PAC,PROTAC-Linker Conjugates for PAC,PROTAC-Linker Conjugates for PAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

157261847