Cbl-b-IN-9

SKU: orb2277581

Description

Cbl-b-IN-9 (Compound 300) is a potent dual inhibitor of Cbl-b and c-Cbl with IC50 values of 5.6 nM and 4.7 nM, respectively. This small molecule is a valuable research tool for investigating E3 ubiquitin ligase function in immunology and oncology, supporting both in vitro biochemical assays and in vivo disease model studies.

Research Area

Cancer Biology, Protein Biochemistry

Key Properties

• CAS Number: 2815223-41-5
• MW: 566.62
• Formula: C₃₀H₃₃F₃N₆O₂
• SMILES: C(C1(COC1)C=2C=C(N=C(C2)C3CC3)N4CC=5C(C4=O)=CC(CNC6(C)CCC6)=CC5C(F)(F)F)C=7N(C)C=NN7
• Target: E1/E2/E3 Enzyme

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

167404364