Cbl-b-IN-5

SKU: orb1944761

Description

Cbl-b-IN-5 is a potent and selective small molecule inhibitor of the E3 ubiquitin ligase Cbl-b, exhibiting IC50 values in the low micromolar range (3-10 µM). It serves as a valuable research tool for investigating the role of Cbl-b in immunological disorders and cancer biology, facilitating both in vitro cellular studies and in vivo disease model research.

Research Area

Cancer Biology, Protein Biochemistry

Key Properties

• CAS Number: 2368835-59-8
• MW: 339.42
• Purity: 99.94% (May vary between batches)
• Formula: C₁₇H₁₇N₅OS
• SMILES: O=C(NC1=CC=CC(=C1)C(SC2=NN=CN2C)C)C3=NC=CC=C3
• Target: E1/E2/E3 Enzyme,Others
• Solubility: DMSO:50 mg/mL (147.31 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.89 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cbl, CblbIN5, Cbl-b-IN-5

Compound Identifiers

PubChem CID

139350067