CB1R antagonist 2

SKU: orb2944984

Description

CB1R antagonist 2 (Compound 11g) is a selective cannabinoid receptor 1 antagonist that blocks the MAPK/NF-κB pathway, demonstrating anti-inflammatory effects in vitro by reducing LPS-induced cytokine production in RAW264.7 cells and in vivo by alleviating OVA-induced allergic rhinitis in murine models.

Research Area

Neuroscience; Pharmacology & Drug Discovery, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• MW: 386.49
• Formula: C₂₄H₂₆N₄O
• Target: p38 MAPK,NF-κB,Cannabinoid Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

p38 MAPK,NF-κB,Cannabinoid Receptor