CB-5339

SKU: orb1689785

Description

p97-IN-1 is a highly potent small molecule inhibitor of the p97 ATPase, demonstrating inhibitory activity with an IC50 below 30 nM. This compound is a valuable research tool for investigating p97 function in protein homeostasis, with applications in both cellular and biochemical studies relevant to cancer and neurodegenerative disease research.

Research Area

Protein Biochemistry

Key Properties

• CAS Number: 1863952-15-1
• MW: 412.49
• Purity: 98.50%
• Formula: C₂₄H₂₄N₆O
• SMILES: CC=1N(C=2C(=C(C(N)=O)C=CC2)C1)C3=NC(NCC4=CC=CC=C4)=C5C(N3)=NCCC5
• Target: p97
• Solubility: DMSO:50 mg/mL (121.22 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:2.5 mg/mL (6.06 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

p97, CB5339, CB-5339, CB 5339, 1HIndole4carboxamide,2methyl1[5,6,7,8tetrahydro4[(phenylmethyl)amino]pyrido[2,3d]pyrimidin2yl]

Compound Identifiers

PubChem CID

122685543