CB-002

SKU: orb692137

Description

CB-002 is a novel small molecule that restores p53 function in mutant p53-expressing colorectal cancer cells without toxicity to normal human fibroblasts; increases expression of endogenous p53 target genes NOXA, DR5, and p21 and cell death; decreases the stability of mutant p53 in RXF393 cancer cells and an exogenously expressed R175H p53 mutant in HCT116 p53-null cells.

Key Properties

• CAS Number: 61034-15-9
• MW: 271.28
• Purity: >98%
• Formula: C₁₃H₁₃N₅O₂
• SMILES: N1C2=C(N(C)C(=O)N(C)C2=O)N=C1NC1=CC=CC=C1

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

378526