Caylin-1

SKU: orb1693712

Description

Caylin-1 is a chlorinated analog of the p53-MDM2 interaction inhibitor Nutlin-3. While less potent in growth inhibition at high doses, it exhibits a unique biphasic effect by promoting HCT116 cell proliferation at low concentrations. This compound is a valuable research tool for studying p53 pathway dynamics and context-dependent cell fate decisions in vitro.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1207480-88-3
• MW: 650.38
• Formula: C₃₀H₂₈Cl₄N₄O₄
• SMILES: C(=O)(N1[C@H]([C@H](N=C1C2=C(OC(C)C)C=C(OC)C=C2)C3=CC(Cl)=C(Cl)C=C3)C4=CC(Cl)=C(Cl)C=C4)N5CC(=O)NCC5
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

99647579