CAY10781

SKU: orb1303815

Description

CAY10781 is a small molecule inhibitor that disrupts the NRP-1/VEGF-A interaction, showing 43% inhibition at 12.5 µM. This compound also reduces VEGF-A-induced VEGFR2 phosphorylation in differentiated CAD cells, making it a useful research tool for studying angiogenesis in cancer and vascular biology models.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 1210360-87-4
• MW: 231.21
• Purity: 99.49% (May vary between batches)
• Formula: C₁₁H₉N₃O₃
• SMILES: OC(=O)CC1=CNC(=NC1=O)C1=CN=CC=C1
• Target: VEGFR,Others
• Solubility: Ethanol:Insoluble;DMF:Insoluble;PBS (pH 7.2):Insoluble;DMSO:10 mg/mL (43.25 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CAY10781, CAY-10781, CAY 10781

Compound Identifiers

PubChem CID

45490125