CAY10747

SKU: orb1693951

Description

CAY10747 is a celastrol-derived inhibitor that disrupts the Hsp90-Cdc37 chaperone complex, leading to reduced client protein levels like p-Akt and Cdk4. It demonstrates anti-proliferative and pro-apoptotic activity in various cancer cell lines, including A549 and MCF-7 cells, supporting its use in oncology research for studying Hsp90-dependent signaling pathways.

Research Area

Cell Biology, Metabolism Research, Signal Transduction

Key Properties

• CAS Number: 2413849-81-5
• MW: 681.83
• Formula: C₄₂H₄₈FNO₆
• SMILES: C[C@@]12[C@](C)([C@]3([C@@](C)(CC1)CC[C@](C(OCCCOC(/C=C(\C#N)/C4=CC=C(F)C=C4)=O)=O)(C)C3)[H])CC[C@]5(C)C2=CC=C6C5=CC(=O)C(O)=C6C
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155513159