CAY10561

SKU: orb1693543

Description

CAY10561 is a potent and selective ATP-competitive inhibitor of ERK2 (Ki=2 nM), a key kinase in the MAPK pathway constitutively active in many cancers. It inhibits proliferation in cellular models like COLO 205 cells (IC50=0.54 µM) and is a valuable tool for studying ERK-driven processes in oncology research.

Research Area

Signal Transduction

Key Properties

• CAS Number: 933786-58-4
• MW: 459.3
• Formula: C₂₂H₁₇Cl₂FN₄O₂
• SMILES: C(NC(CO)C1=CC(Cl)=C(F)C=C1)(=O)C2=CC(C=3C(=CNN3)C4=CC(Cl)=CC=C4)=CN2
• Target: ERK,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

135523966