CAY10448

SKU: orb1692691

Description

Capsaicin, the lipophilic compound responsible for the pungency of chili peppers, activates the TRPV1 (VR1) ion channel. CAY10448 is a potent iodinated nonivamide derivative that antagonizes this receptor with an IC50 of ~10 nM. This antagonist is widely used in vitro and in vivo to study TRPV1-mediated pain, neurogenic inflammation, and thermoregulation.

Key Properties

• CAS Number: 1177195-52-6
• MW: 433.32
• Formula: C₁₈H₂₈INO₃
• SMILES: C(NC(CCCCCCC(C)C)=O)C1=CC(OC)=C(O)C=C1I
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

35026498