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β-Catenin modulator-7

SKU: orb2663975

Description

β-Cateninmodulator-7 is a small molecule inhibitor of β-catenin signaling, suppressing its expression and inhibiting GSK-3β phosphorylation in HCT-116 colon cancer cells. It induces nitric oxide release and demonstrates anti-proliferative activity (IC50 0.6-0.9 µM), making it a useful research tool for studying Wnt/β-catenin pathway in colorectal cancer models.

Images & Validation

Key Properties

CAS Number2892294-93-6
MW583.03
FormulaC26H35ClN4O9
SMILESO=C(OCON=N(=O)N(CC)CC)CCCCOC1=C(OC)C=C(C=CC(=O)N2C(=O)C(Cl)=CCC2)C=C1OC

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information