β-catenin-IN-37

SKU: orb1691493

Description

β-Catenin-IN-37 is a selective small molecule inhibitor that disrupts the β-catenin/Tcf protein-protein interaction, thereby blocking canonical Wnt signaling. It demonstrates anti-proliferative activity in colorectal cancer cell lines such as SW480 and HCT116, with IC50 values of 20 μM and 31 μM, respectively, making it a useful tool for oncology and Wnt pathway research.

Research Area

Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1783856-40-5
• MW: 307.277
• Formula: C₁₃H₉N₉O
• SMILES: C(Cn1c2ccccc2c2nc3nonc3nc12)c1nnn[nH]1
• Target: Wnt/beta-catenin,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

122180712