β-catenin-IN-3

SKU: orb1908992

Description

β-catenin-IN-3 is a potent and selective small molecule inhibitor of β-catenin, binding with high affinity (K_D = 54.96 nM) to a cryptic regulatory site. It effectively suppresses the viability of β-catenin-dependent cancer cells in vitro, making it a valuable chemical probe for studying Wnt/β-catenin signaling in oncology research.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1005288-15-2
• MW: 484.25
• Formula: C₁₉H₂₀Br₂N₂OS
• SMILES: N(C(NC=CC1=C(O)C(Br)=CC(Br)=C1)=S)C2C3C4C(C(C3)C2)CC=C4
• Target: CDK,Others,Wnt/beta-catenin

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

3003888