Caspase-3 activator 1

SKU: orb2277717

Description

Caspase-3 activator 1 (compound 4b) is a ruthenium-based complex that suppresses gastric cancer progression by activating caspase-3-mediated cleavage of gasdermin E, triggering tumor cell pyroptosis. This mechanism promotes anti-tumor immune responses and has demonstrated efficacy in both cellular and animal models of gastric cancer. It can be co-delivered with decitabine via a liposomal system.

Research Area

Cell Biology, Immunology & Inflammation

Images & Validation

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Key Properties

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MW	644.75
Formula	C₂₈H₂₇N₆O₂RuS₂
Target	Pyroptosis

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Pyroptosis

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