Casein kinase 1δ-IN-29

SKU: orb2944400

Description

Casein kinase1δ-IN-29 is a potent dual inhibitor of p38α and CK1δ/ε kinases, demonstrating sub-micromolar IC50 values. It induces subG1 cell cycle arrest and apoptosis in AC1-M88 cells, making it a useful chemical probe for studying kinase signaling in cellular proliferation and death pathways.

Research Area

Cell Biology, Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1177418-39-1
• MW: 506.549
• Formula: C₂₆H₂₃FN₄O₄S
• SMILES: S(C)(=O)C=1NC(=C(N1)C2=CC=C(F)C=C2)C=3C=C(NC(/C=C/C4=C(OC)C=C(OC)C=C4)=O)N=CC3
• Target: Apoptosis,Casein Kinase,p38 MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

44597227