Casein kinase 1δ-IN-27

SKU: orb2944681

Description

Casein kinase1δ-IN-27 is a potent, low-nanomolar inhibitor of CK1 isoforms (α, δ, ε) and p38α, and it suppresses DUX4 expression. This compound is a valuable research tool for studying kinase signaling pathways and has been utilized in cellular models relevant to facioscapulohumeral muscular dystrophy (FSHD) research.

Research Area

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1095706-65-2
• MW: 374.414
• Formula: C₂₁H₁₉FN₆
• SMILES: FC1=CC=C(C=C1)C=2N=C3C=CC(=NN3C2C=4C=CN=CC4)N5CCNCC5
• Target: Casein Kinase,p38 MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

25183292