Carglumic Acid

SKU: orb1310321

Description

Carglumic Acid is an orphan drug approved by the U.S. FDA in 2010 for treating hyperammonemia caused by N-acetylglutamate synthase deficiency. It serves as a replacement activator for carbamoyl phosphate synthetase 1, facilitating ammonia detoxification via the urea cycle, and is utilized in both clinical management and related biochemical research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1188-38-1
• MW: 190.15
• Purity: 99.93% (May vary between batches)
• Formula: C₆H₁₀N₂O₅
• SMILES: [C@@H](CCC(O)=O)(NC(N)=O)C(O)=O
• Target: Others
• Solubility: DMSO:45 mg/mL (236.66 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (10.52 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Carbamino-L-glutamic acid, Carbamoyl-phosphate synthase, Carbamylglutamic acid, Carbaglu, Carglumic Acid, N-Carbamylglutamate, N-Carbamyl-L-glutamic acid, inhibit, Inhibitor, Ureidoglutaric acid

Compound Identifiers

PubChem CID

121396