Carboxylesterase-IN-3

SKU: orb1689242

Description

Carboxylesterase-IN-3 is a potent and selective Notum carboxylesterase inhibitor with an IC50 of ≤10 nM. This small molecule is a valuable research tool for investigating the role of Notum in Wnt signaling pathways, with applications in oncology research for both in vitro and in vivo studies.

Research Area

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2764748-92-5
• MW: 313.16
• Purity: 98.47% (May vary between batches)
• Formula: C₁₁H₆Cl₂N₄OS
• SMILES: O=C1N2C(C=CC(SC3=CC(Cl)=C(Cl)C=C3)=N2)=NN1
• Target: Lipid,Wnt/beta-catenin
• Solubility: DMSO:3.14 mg/mL (10.03 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Carboxylesterase, bcatenin, beta-catenin, betacatenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, βcatenin

Compound Identifiers

PubChem CID

162394533