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Carboxylesterase-IN-2

SKU: orb1819086

Description

Carboxylesterase-IN-2 is a potent and selective Notum carboxylesterase inhibitor with an IC50 of ≤10 nM. This compound is a valuable research tool for investigating the role of Notum in Wnt signaling pathways, with applications in cancer-related in vitro and in vivo studies.

Research Area

Metabolism Research, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number2764748-88-9
MW272.33
Purity>99.99% (May vary between batches)
FormulaC13H12N4OS
SMILESO=C1N2C(C=CC(SC3=CC(C)=C(C)C=C3)=N2)=NN1
TargetLipid,Wnt/beta-catenin
SolubilityDMSO:70 mg/mL (257.04 mM)

Bioactivity

Target IC50
Carboxyl esterase Notum:<10 nM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Carboxylesterase, Carboxylesterase-IN-2, betacatenin, beta-catenin, 1,2,4Triazolo[4,3b]pyridazin3(2H)one,6[(3,4dimethylphenyl)thio], bcatenin, Wnt, Wnt/b-catenin, Wnt/betacatenin, Wnt/β-catenin, βcatenin

Similar Products

  • Carboxylesterase-IN-2 [orb2900499]

    >98% (HPLC)

    2764748-88-9

    272.33

    C13H12N4OS

    500 mg, 1 g, 10 mg, 25 mg, 50 mg, 100 mg, 2 mg, 5 mg
Quality Guarantee

Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 100.00
5 mg
$ 190.00
1 ml x 10 mM (in DMSO)
$ 200.00
10 mg
$ 270.00
25 mg
$ 430.00
50 mg
$ 580.00
100 mg
$ 780.00
200 mg
$ 1,040.00
DispatchUsually dispatched within 5-10 working days
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