Carbobenzoxyphenylalanine

SKU: orb1219349

Description

Carbobenzoxyphenylalanine is a thermolysin inhibitor.The protease can be inhibited by the serine specific reagents phenylmethanesulfonyl fluoride and diisopropyl fluorophosphate and the alkylating reagent, carbobenzoxyphenylalanine chloromethyl ketone, in the presence of organic solvents at 1 mM concentration. The inhibitions of chromatin-bound protease in rat liver by these compounds are irreversible. On the other hand, carbobenzoxyphenylalanine and p-nitrophenyl acetate were shown to be reversible inhibitors of rat liver chromatin-bound protease.

Key Properties

• CAS Number: 1161-13-3
• MW: 299.32
• Purity: >98% (HPLC)
• Formula: C₁₇H₁₇NO₄
• SMILES: C1=CC=C(C=C1)CC(C(=O)O)NC(=O)OCC2=CC=CC=C2
• Target: thermolysin
• Solubility: DMSO:Soluble

Bioactivity

• In Vitro:
  Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances.

Storage & Handling

• Storage: Storage temperature: -20°C. Stability: ≥ 2 years
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Carbobenzoxy-L-phenylalanine,NSC 402059,NSC-402059

Quick Database Links

Gene Symbol

thermolysin