Carabrone

SKU: orb1297548

Description

Carabrone is a bicyclic sesquiterpenic lactone of botanical origin with promising fungicidal activity. It effectively controls Gaeumannomyces tritici, the causative agent of take-all root rot in wheat, and is used in agricultural fungicide research.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 1748-81-8
• MW: 248.32
• Purity: 99.72% (May vary between batches)
• Formula: C₁₅H₂₀O₃
• SMILES: [H][C@@]12C[C@]3([H])C(=C)C(=O)O[C@]3([H])C[C@]1(C)[C@H]2CCC(C)=O
• Target: Antibacterial|||Antifection
• Solubility: DMSO:60 mg/mL (241.62 mM);H2O:< 1 mg/mL (insoluble);10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (20.14 mM)

Bioactivity

• Target IC50:
  Colletotrichum lagenarium:7.10 μg/mL (EC50)
• In Vitro:
  To continuously improve the potential utility of the natural lead compound of Carabrone in agrochemistry, Carabrone oxime and 36 novel oxime ester derivatives of Carabrone modified at C(4) were synthesized, and evaluated for their antifungal activities against Botrytis cinerea in vitro and in vivo
  Read more...

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Bacterial, Antifection, Carabrone, Inhibitor, inhibit

Compound Identifiers

PubChem CID

164879