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CAR-2

SKU: orb2944496

Description

CAR-2 is a BODIPY-derived photosensitizer that selectively targets the endoplasmic reticulum and lipid droplets to induce ferroptosis upon light activation. It demonstrates potent in vitro phototoxicity against breast cancer cells (IC50 0.01-0.02 µM) and has shown significant antitumor efficacy in a 4T1 mouse xenograft model.

Research Area

Cell Biology, Immunology & Inflammation, Metabolism Research, Signal Transduction

Images & Validation

Key Properties

CAS Number3030055-40-1
MW738.114
FormulaC27H23BF2I2N4O2
SMILESO=C(OC)C=1N=C(C2=C3C(=C(I)C(=[N]3[B+3]([F-])([F-])[N-]4C2=C(C(I)=C4C)C)C)C)C5=C(C1)C=6C=CC=CC6N5C
TargetFerroptosis,Reactive Oxygen Species,Photosensitizer

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information