Cantharidic acid

SKU: orb3134468

Description

Cantharidic acid is a selective inhibitor of protein phosphatase 2 (PP2A) and protein phosphatase 1 (PP1). It impedes cell viability by upregulating the ERK1/2, p38, and JNK1/2 pathways, causes cell cycle arrest at the sub-G1 phase, and induces apoptosis in NPC-39 and HONE-1 cells.

Key Properties

• CAS Number: 28874-45-5
• MW: 214.22
• Formula: C₁₀H₁₄O₅
• SMILES: C(O)(=O)[C@@]1(C)[C@](C(O)=O)(C)[C@]2(O[C@@]1(CC2)[H])[H]
• Target: Apoptosis,JNK,Phosphatase,ERK,p38 MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,JNK,Phosphatase,ERK,p38 MAPK