Canine COL6A6 Protein, His Tag

SKU: orb3158251

Description

COL6A6 belongs to the type VI collagen family and is an extracellular matrix component highly expressed in the lungs, adipose tissue, and skeletal muscle. It provides structural support and regulates signaling by inhibiting the PI3K-Akt pathway to play a tumor-suppressive role. Its abnormalities are closely linked to skin inflammation, retinitis pigmentosa, and pituitary adenoma, making it a potential diagnostic marker or therapeutic target.

Images & Validation

• Application Notes:
  This protein carries a polyhistidine tag at the N-terminus. The protein has a calculated MW of 62.8 kDa. The protein migrates as 65-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

• Expression System: HEK293
• Target: COL6A6
• Reactivity: Canine
• Tag: N-10×His
• Expression Region: Asp 437 - Val 983
• Conjugation: Unconjugated
• MW: 62.8 kDa
• Purity: 90%

Storage & Handling

• Storage: -20°C
• Form/Appearance: Powder
• Buffer/Preservatives: PBS, pH 7.4
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

COL6A6

RefSeq:A0A8C0PIB6