CAD204520

SKU: orb2665515

Description

CAD204520 is a SERCA inhibitor (IC50 = 0.34 µM) that selectively targets mutant NOTCH1 proteins linked to T-ALL and MCL. It serves as a valuable research tool for investigating NOTCH1-driven oncogenesis in both cellular and animal models of these hematological cancers.

Research Area

Metabolism Research, Neuroscience, Pharmacology & Drug Discovery, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 2682205-20-3
• MW: 439.51
• Formula: C₂₃H₃₂F₃N₃O₂
• SMILES: FC(F)(F)OC=1C=CC2=C(C1)NC(=C2CCC)C3N(CCN4CCOCC4)CCCC3
• Target: Calcium Channel,Gamma-secretase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155293044