C8 D-threo Ceramide (d18:1/8:0)

SKU: orb1693841

Description

C8 D-threo Ceramide is a cell-permeable, cytotoxic ceramide analog that potently induces DNA fragmentation and activates ceramide-activated protein kinase (CAPK) in U937 cells. It serves as a substrate for E. coli diacylglycerol kinase and enhances pore formation by V. cholerae cytolysin in lipid membrane models, supporting research in sphingolipid signaling, apoptosis, and bacterial toxin mechanisms.

Research Area

Cell Biology

Key Properties

• CAS Number: 175892-43-0
• MW: 425.698
• Formula: C₂₆H₅₁NO₃
• SMILES: CCCCCCCCCCCCC\C=C\[C@@H](O)[C@@H](CO)NC(=O)CCCCCCC
• Target: Others,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

97043297