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Catalog Number | orb1692138 |
---|---|
Category | Small Molecules |
Description | C24 Phytosphingosine (t18:0/24:0) |
CAS Number | 34437-74-6 |
Purity | 98% |
MW | 668.13 |
SMILES | [C@H]([C@@H]([C@@H](CCCCCCCCCCCCCC)O)O)(NC(CCCCCCCCCCCCCCCCCCCCCCC)=O)CO |
Formula | C42H85NO4 |
Biological Activity | C24 Phytosphingosine (t18:0/24:0) is a phytoceramide, which is a family of sphingolipids found in the intestine, kidney, and extracellular spaces of the stratum corneum of the mammalian epidermis. C24 Phytosphingosine (t18:0/24:0) is composed of a phytosphingosine backbone amine-linked to a C24 fatty acid chain. It has been used with other ceramides to create stratum corneum substitutes to study percutaneous penetration and psoriasis in vitro. In a stratum corneum model of healthy skin, the incorporation of long-chain-containing phytoceramides, such as C24 phytosphingosine (t18:0/24:0), increases permeability of the membrane in comparison with incorporation of dihydroceramides. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |