C188

SKU: orb1700931

Description

C188 is a cell-permeable, small-molecule STAT3 inhibitor that selectively blocks IL-6-induced STAT3 phosphorylation and nuclear translocation by targeting its SH2 domain. It is a valuable research tool for studying STAT3-dependent signaling in cancer and inflammation, with demonstrated utility in both in vitro and in vivo models.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 823828-18-8
• MW: 433.45
• Formula: C₁₉H₁₅NO₇S₂
• SMILES: OC(=O)CSc1cc(NS(=O)(=O)c2ccc(cc2)C(O)=O)c2ccccc2c1O
• Target: Apoptosis,STAT,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

1652812