c-Met/HDAC-IN-2

SKU: orb1744685

Description

c-Met/HDAC-IN-2 is a dual-action small molecule with potent inhibitory activity against c-Met (IC50=5.40 nM) and HDAC1 (IC50=18.49 nM). It demonstrates robust anti-proliferative effects in vitro, inducing cell cycle arrest and apoptosis in cancer cell lines like HCT-116, supporting its investigation for overcoming therapeutic resistance.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 2740495-53-6
• MW: 623.66
• Formula: C₃₄H₃₃N₅O₇
• SMILES: O(C=1C2=C(C=C(OCCCCCCC(NO)=O)C(OC)=C2)N=CC1)C3=CC=C(NC(=O)C4=NN(C=CC4=O)C5=CC=CC=C5)C=C3
• Target: Others,HDAC,c-Met/HGFR,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162656698