C-Met/Axl-IN-1

SKU: orb2944601

Description

C-Met/Axl-IN-1 (Compound 22a) is an orally bioavailable, selective type II inhibitor targeting c-Met (IC50=1 nM) and Axl (IC50=10 nM). It demonstrates potent anti-tumor activity by inhibiting proliferation, inducing cell cycle arrest, and promoting apoptosis in cellular assays, supporting its use in oncology research.

Research Area

Cell Biology, Signal Transduction

Key Properties

• MW: 472.45
• Formula: C₂₅H₁₈F₂N₆O₂
• Target: Apoptosis,c-Met/HGFR,TAM Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,c-Met/HGFR,TAM Receptor