c-Met-IN-14

SKU: orb1744491

Description

c-Met-IN-14 is a potent and selective N-sulfonylamidine-based c-Met kinase inhibitor (IC50 = 2.89 nM). It exerts anticancer effects by blocking c-Met phosphorylation, inducing G2/M cell cycle arrest, and promoting apoptosis in A549 cells in vitro, making it a valuable tool for oncology research.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2443380-34-3
• MW: 701.2
• Formula: C₃₄H₃₈ClFN₄O₇S
• SMILES: O(C=1C2=C(C=C(OCCCN3CCOCC3)C(OC)=C2)N=CC1)C4=C(F)C=C(N=C(NS(CC5=CC=C(Cl)C=C5)(=O)=O)CCOC)C=C4
• Target: Others,FLT,c-Met/HGFR,Apoptosis,c-Kit

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171975637