c-Kit-IN-12

SKU: orb3174875

Description

c-Kit-IN-12 (Compound 2a) is a potent c-Kit inhibitor with an IC50 of less than 10 nM across four KIT mutant cell models [BAF3 KIT EX11 DEL, EX11 DEL/D816H, EX11 DEL/T670I, EX11 DEL/V654A]. It is useful for research into c-Kit-associated diseases or disorders, such as cancer.

Key Properties

• CAS Number: 2797973-68-1
• MW: 515.51
• Formula: C₂₄H₂₀F₃N₅O₃S
• SMILES: C(NC1=CC(C#CC=2SC(NC(=O)N3C[C@H](O)CC3)=NC2)=C(C)C=C1)(=O)C4=CC(C(F)(F)F)=CC=N4
• Target: c-Kit

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

c-Kit