Bz-Nle-Lys-Arg-Arg-AMC

• Catalog Number: orb1692512
• Category: Small Molecules
• Description: Bz-Nle-Lys-Arg-Arg-AMC
• CAS Number: 863975-32-0
• Purity: 98%
• MW: 832.99
• SMILES: CC=1C=2C(=CC(NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC(=O)C3=CC=CC=C3)CCCC)=O)CCCCN)=O)CCCNC(=N)N)=O)CCCNC(=N)N)=O)=CC2)OC(=O)C1
• Formula: C₄₁H₆₀N₁₂O₇
• Biological Activity: Substrate for dengue virus NS2B-NS3 and yellow fever virus NS3 protease. The kcat/Km value of Bz-NleKRR-AMC for the dengue virus type 4 (DEN4) enzyme is > 800 fold higher than that of Boc-Gly-Arg-Arg-AMC, a widely used NS3 substrate (kcat = 2.9 s 1, Km = 8.6 μM for DEN4). For yellow fever virus NS3 protease the kcat value was 0.111 s 1, the Km value 14.6 μM.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.