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BX517

SKU: orb1303249

Description

BX517 is a potent and selective small molecule inhibitor targeting PDK1. It is a valuable research tool for studying PI3K/AKT signaling pathways in cancer biology, applicable in both cellular and biochemical in vitro assays.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number850717-64-5
MW282.3
Purity99.26% (May vary between batches)
FormulaC15H14N4O2
SMILESC\C(=C1\C(=O)Nc2ccc(NC(N)=O)cc12)c1ccc[nH]1
TargetPDK,Akt
Solubility10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.08 mM);DMSO:50 mg/mL (177.12 mM)

Bioactivity

Target IC50
PDX1:6 nM

Storage & Handling

StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

Akt2, BX517, BX-517, BX 517, inhibit, Inhibitor, PDK-1, PDK1, PDK1 inhibitor 2
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

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Protocol Information

BX517 (orb1303249)

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% DMSO +
%+
% Tween 80 +
%

Available Sizes

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1 mg
$ 80.00
1 ml x 10 mM (in DMSO)
$ 110.00
5 mg
$ 110.00
10 mg
$ 130.00
25 mg
$ 200.00
50 mg
$ 330.00
100 mg
$ 500.00
DispatchUsually dispatched within 3-5 working days
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