BX-320

SKU: orb1692786

Description

BX-320 is a potent and selective PDK1 inhibitor (IC50=30 nM) that suppresses downstream Akt and p70S6K phosphorylation in vitro. It induces apoptosis and inhibits proliferation in various cancer cell lines and demonstrates in vivo efficacy by reducing lung tumor growth in a mouse metastasis model.

Research Area

Signal Transduction

Key Properties

• CAS Number: 702676-93-5
• MW: 547.45
• Formula: C₂₃H₃₁BrN₈O₃
• SMILES: CC(C)(C(N)=O)C(=O)NCCCNC1=NC(NC2=CC=CC(NC(=O)N3CCCC3)=C2)=NC=C1Br
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

657138