BVB808

SKU: orb2664356

Description

BVB808 is a potent and selective JAK2 inhibitor, demonstrating approximately 10-fold selectivity over other JAK family members in vitro. It blocks JAK2-STAT5 signaling, inhibiting proliferation and survival in dependent cell lines, and is a valuable tool for investigating JAK2-driven hematological cancers in preclinical research.

Key Properties

• CAS Number: 1414587-22-6
• MW: 533.62
• Formula: C₂₉H₃₃F₂N₇O
• SMILES: N(C=1N=C2N(C=CC2=CN1)C3=CC(F)=C(CN4CCOCC4)C(F)=C3)C5=CC=C(C=C5)N6C[C@@H](C)N[C@@H](C)C6

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90480481