Butyl isobutyl phthalate

SKU: orb1299040

Description

Butyl isobutyl phthalate is a non-competitive α-glucosidase inhibitor with an IC50 of 38 µM. This activity underpins its investigation as a potential hypoglycemic agent in diabetes-related research, utilizing both in vitro enzymatic assays and in vivo metabolic studies.

Research Area

Metabolism Research

Key Properties

• CAS Number: 17851-53-5
• MW: 278.34
• Purity: 98.00% (May vary between batches)
• Formula: C₁₆H₂₂O₄
• SMILES: CCCCOC(=O)c1ccccc1C(=O)OCC(C)C
• Target: glycosidase,Glucosidase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (17.96 mM);DMSO:250 mg/mL (898.18 mM)

Bioactivity

• Target IC50:
  α-glucosidase:38 μM
• In Vivo:
  Butyl isobutyl phthalate(BIP) could be considered as an α-glucosidase inhibitor and developed as an important antidiabetes agent for type II diabetes therapy.
  Read more...
• Animal Research:
  Animal Model:Streptozocin induced diabetic mice (Male Kunming mice). Dosage:25, 50 or 100 mg/kg, Administration:Intragastric administration

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

diabete, Butyl isobutyl Phthalate, Butyl isobutyl phthalate, ButylIsobutylPhthalate, hypoglycemic, Inhibitor, Glucosidase, inhibit, α-glucosidase

Compound Identifiers

PubChem CID

28813