BTSA1.2

SKU: orb1146690

Description

BTSA1.2 is a rationalized BTSA1 analog with improved binding to BAX, cellular cytotoxicity, and better toleratence in vivo. Combination of BTSA1.2 with Navitoclax demonstrates synergistic efficacy in apoptosis-resistant cancer cells, xenografts, and patient-derived tumors while sparing healthy tissues.

Key Properties

• CAS Number: 2254256-66-9
• MW: 458.56
• Purity: >98%
• Formula: C₂₃H₁₈N₆OS₂
• SMILES: O=C1N(N=C(C=2C=CC=CC2)C1N=NC3=NC(=C(S3)C)C)C4=NC(=CS4)C=5C=CC=CC5

Storage & Handling

• Expiration Date: 12 months from date of receipt.
• Hazard Information: Non-Toxic
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162639985