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BTK inhibitor 19

SKU: orb1690778

Description

BTK inhibitor 19 is a potent and selective covalent inhibitor of Bruton's tyrosine kinase with an IC50 of 2.7 nM. It is a valuable research tool for investigating B-cell signaling pathways and has demonstrated utility in both in vitro biochemical assays and in vivo models of autoimmune and inflammatory diseases.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery; Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number2557174-19-1
MW527.508
FormulaC25H24F3N7O3
SMILESNC(=O)c1c(nc([C@@H]2CCCCN2C(=O)C=C)n1N)-c1ccc(cc1)C(=O)Nc1cc(ccn1)C(F)(F)F
TargetBTK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information