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BTK-IN-22

SKU: orb1744306

Description

BTK-IN-22 is a potent and selective small molecule inhibitor of BTK (IC50: 0.9 nM), with additional activity against BLX and BMX. It demonstrates superior kinase selectivity compared to Ibrutinib. This inhibitor is a valuable chemical probe for studying B-cell signaling pathways in both cellular and biochemical assays.

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

Key Properties

CAS Number2573048-10-7
MW454.52
FormulaC26H26N6O2
SMILESNC1=C2C(=NN(C2=NC=N1)[C@H]3CN(C(C=C)=O)CCC3)C4=C(C)C=C(OC5=CC=CC=C5)C=C4
TargetBTK,Others

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Key Properties

No computed properties available.

Protocol Information