BT-GSI

SKU: orb1744129

Description

BT-GSI is a bone-targeting γ-secretase inhibitor that blocks Notch signaling. It demonstrates dual anti-myeloma and anti-resorptive activity in research, showing potential to inhibit tumor progression and osteolytic lesions in preclinical models of multiple myeloma and bone metastatic disease.

Research Area

Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• MW: 730.52
• Formula: C₂₆H₄₆BrN₅O₁₀P₂
• SMILES: CC[C@H](C)[C@@H](C(=O)N[C@@H](CC(C)C)/C=N/N(C)CCCC(=O)NC(P(=O)(O)O)P(=O)(O)O)NC(=O)OCC1=CC=CC=C1.Br
• Target: Others,Gamma-secretase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

163196438