BS194

SKU: orb1299582

Description

BS194 is a potent and selective small molecule inhibitor of cyclin-dependent kinases (CDKs). It is a valuable research tool for studying cell cycle progression and proliferation in both in vitro and in vivo models of cancer and other proliferative diseases.

Research Area

Cell Biology

Key Properties

• CAS Number: 1092443-55-4
• MW: 385.46
• Purity: 99.85% (May vary between batches)
• Formula: C₂₀H₂₇N₅O₃
• SMILES: C(C)(C)C1=C2N(C(NCC3=CC=CC=C3)=CC(N[C@H]([C@@H](CO)O)CO)=N2)N=C1
• Target: CDK
• Solubility: DMSO:27.5 mg/mL (71.34 mM)

Bioactivity

• Target IC50:
  CDK5:30 nM|CDK1:30 nM|CDK7:250 nM|CDK2:3 nM|CDK9:90 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Cyclin dependent kinase, CDKs, CDK, colon cancer, breast cancer, BS 194, BS194, BS-194, anti-cancer, Antitumor, Inhibitor, HCT-116, MCF-7, inhibit, xenografts, retinoblastoma

Compound Identifiers

PubChem CID

25125014