Brompheniramine maleate

SKU: orb1310837

Description

Dimotane (Brompheniramine maleate) is a selective histamine H1 receptor antagonist. It is widely used in pharmacological research to study allergic responses and histamine signaling pathways, both in vitro and in animal models.

Research Area

Immunology & Inflammation, Metabolism Research, Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 980-71-2
• MW: 435.31
• Purity: >99.99% (May vary between batches)
• Formula: C₁₆H₁₉BrN₂·C₄H₄O₄
• SMILES: OC(=O)/C=C\C(=O)O.CN(C)CCC(c1ccc(Br)cc1)c1ccccn1
• Target: Potassium Channel,AChR,Calcium Channel,Sodium Channel,Histamine Receptor,5-HT Receptor
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.58 mM);H2O:42 mg/mL (96.48 mM);Ethanol:15 mg/mL (34.46 mM);DMSO:81 mg/mL (186.07 mM)

Bioactivity

• Target IC50:
  H1 receptor:6.06 nM (Kd)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Muscarinic acetylcholine receptor, inhibit, KcsA, mAChR, Na+ channels, Na channels, Inhibitor, HistamineReceptor, Histamine Receptor, HT, 5HTReceptor, (±)-Brompheniramine, allergic rhinitis, 5HT Receptor, anticholinergic, antidepressant, antihistamine, Calcium Channel, Ca2+ channels, Ca channels, Brompheniramine, Brompheniramine hydrogen Maleate, Brompheniramine hydrogen maleate, Brompheniramine maleate, Brompheniramine Maleate, common cold, Dimetane, Dimotane, sedative, Potassium Channel, Rolabromophen, Sodium Channel

Compound Identifiers

PubChem CID

5281067