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Bromodomain inhibitor-13

SKU: orb2665548

Description

Bromodomain Inhibitor-13 (Compound 1), an analog of PFI-3, is a bromodomain-containing protein (BCP) inhibitor. It specifically targets the bromodomains of SMARCA2, SMARCA4, and the first and second bromodomains of PB1 [PB1(5) and PB1(2)], with dissociation constants (KD) of 37, 53, 30, and 190 nM, respectively.

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Key Properties

CAS Number1914047-59-8
MW362.43
FormulaC21H22N4O2
SMILESN(C1=C2C([C@@]3(N(/C=C/C(=O)C4=C(O)C=CC=C4)[C@](C2)(CC3)[H])[H])=NC=N1)C5CC5
TargetEpigenetic Reader Domain

Storage & Handling

Storage-20°C
DisclaimerFor research use only
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Bromodomain inhibitor-13 (orb2665548)

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