BRM/BRG1 ATP Inhibitor-3

SKU: orb1745019

Description

BRM/BRG1 ATP Inhibitor-3 is a potent, dual-targeting small molecule that inhibits the BRM and BRG1 ATPases of the BAF complex with IC50 values of 10.4 nM and 19.3 nM, respectively. It is a valuable chemical probe for studying chromatin remodeling in cancer research and other BAF-related diseases, with utility in both in vitro and in vivo experimental models.

Research Area

Epigenetics & Chromatin, Neuroscience; Epigenetics & Chromatin; Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2368901-31-7
• MW: 503.64
• Formula: C₂₆H₂₅N₅O₂S₂
• SMILES: N(C([C@@H](NC(=O)C1=CC=C(N)C=C1)CCSC)=O)C2=NC(C3=CC(=CC=C3)C=4C=CN=CC4)=CS2
• Target: Epigenetic Reader Domain,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

139370707