BRM/BRG1 ATP-IN-8

SKU: orb3173789

Description

BRM/BRG1 ATP-IN-8 (Compound Cpd14) is an orally effective inhibitor of the BRG1/BRM enzyme domain. It exerts antitumor effects by disrupting aberrant chromatin remodeling in cancer cells, inducing apoptosis, and causing growth arrest. This compound is promising for research on BRG1/BRM-dependent malignancies, including hematologic cancers, prostate cancer, breast cancer, and Ewing's sarcoma.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2468046-72-0
• MW: 565.62
• Formula: C₂₆H₂₃N₅O₆S₂
• SMILES: O=C(O)C1(C2=NC=CC(=C2)C3=CC=CC(=C3)C=4N=C(SC4)NC(=O)CNC(=O)C=5C=CN(C5)S(=O)(=O)C)CC1
• Target: Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Epigenetic Reader Domain